ICD-10-CM 2027 diagnosis code
E80Disorders of porphyrin and bilirubin metabolism
E80 is a header code, so it can't be reported by itself. Choose one of the 8 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E80
E80 is the ICD-10-CM diagnosis code for disorders of porphyrin and bilirubin metabolism. It belongs to block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 8 subcodes must be used instead.
To report this condition, pick the subcode that matches the documentation: E80.0 (porphyria), E80.1 (tarda), E80.2 (porphyria), E80.3 (peroxidase), E80.4 (syndrome), E80.5 (syndrome), E80.6 (metabolism) and E80.7 (unspecified).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under E80
- E80.0Hereditary erythropoietic porphyriaBillable
- E80.1Porphyria cutanea tardaBillable
- E80.2Other and unspecified porphyria
- E80.3Defects of catalase and peroxidaseBillable
- E80.4Gilbert syndromeBillable
- E80.5Crigler-Najjar syndromeBillable
- E80.6Other disorders of bilirubin metabolismBillable
- E80.7Disorder of bilirubin metabolism, unspecifiedBillable
Coding notes
- defects of catalase and peroxidase
Notes that apply from higher levels
Instructions written at a parent level also apply to E80.
Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E80
Is E80 billable?
- No. E80 is a header code. Report one of its more specific subcodes instead.