ICD-10-CM 2027
ICD-10 code for Cholesteremia
From the official ICD-10-CM alphabetic index entry “Cholesteremia”. Page updated September 29, 2026.
About coding Cholesteremia
The ICD-10-CM code for Cholesteremia is E78.00 (Pure hypercholesterolemia, unspecified).
Within E78.0, choose E78.00 (unspecified) only when documentation doesn't support a more specific option: familial hypercholesterolemia (E78.01).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Cholesteremia ICD-10 codes
What is the ICD-10 code for Cholesteremia?
- E78.00 — Pure hypercholesterolemia, unspecified.
Is E78.00 billable?
- Yes. E78.00 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E78.00 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E78.00 as a principal diagnosis.
Is E78.00 a CC or MCC?
- No. E78.00 is neither a CC nor an MCC under MS-DRG v44.0.