Skip to content
Dx

ICD-10-CM 2027 diagnosis code

E78.01Familial hypercholesterolemia

Not billable — use a more specific code

E78.01 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it.

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E78.01

E78.01 is the ICD-10-CM diagnosis code for familial hypercholesterolemia. It belongs to category E78 (disorders of lipoprotein metabolism and other lipidemias), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within E78.0 (pure hypercholesterolemia), E78.01 is specifically for familial hypercholesterolemia. Related codes cover unspecified (E78.00).

To report this condition, pick the subcode that matches the documentation: E78.010 ([HoFH]), E78.011 ([HeFH]) and E78.019 (unspecified).

It was added in FY2017, effective October 1, 2016, and changed in FY2026.

Before ICD-10, this condition was coded in ICD-9-CM as 272.0 (pure hypercholesterolemia).

Specific codes under E78.01

Notes that apply from higher levels

Instructions written at a parent level also apply to E78.01.

› From E78 Disorders of lipoprotein metabolism and other lipidemias
Excludes1

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

ICD-9-CM equivalent

Converter →
  • 272.0Pure hypercholesterolemiaapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2017 (effective 10/1/2016): Added
  • FY2026 (effective 10/1/2025): Expanded — no longer billable

Common questions about E78.01

Is E78.01 billable?

No. E78.01 is a header code. Report one of its more specific subcodes instead.

What is the ICD-9 code for E78.01?

The CMS General Equivalence Mappings map E78.01 to ICD-9-CM 272.0.