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ICD-10-CM 2027 diagnosis code

E78.0Pure hypercholesterolemia

Not billable — use a more specific code

E78.0 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it.

Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS, effective October 1, 2026. Updated September 29, 2026. About our data

About E78.0

E78.0 is the ICD-10-CM diagnosis code for pure hypercholesterolemia. It belongs to category E78 (disorders of lipoprotein metabolism and other lipidemias), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.

Within E78 (disorders of lipoprotein metabolism and other lipidemias), E78.0 is specifically for pure hypercholesterolemia. Related codes cover pure hyperglyceridemia (E78.1), mixed hyperlipidemia (E78.2), Hyperchylomicronemia (E78.3), other hyperlipidemia (E78.4), hyperlipidemia, unspecified (E78.5), lipoprotein deficiency (E78.6), disorders of bile acid and cholesterol metabolism (E78.7), other disorders of lipoprotein metabolism (E78.8) and 1 more.

To report this condition, pick the subcode that matches the documentation: E78.00 (unspecified) and E78.01 (hypercholesterolemia).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2017 (expanded into subcodes).

Specific codes under E78.0

Notes that apply from higher levels

Instructions written at a parent level also apply to E78.0.

› From E78 Disorders of lipoprotein metabolism and other lipidemias
Excludes1

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • FY2017 (effective 10/1/2016): Expanded — no longer billable

Common questions about E78.0

Is E78.0 billable?

No. E78.0 is a header code. Report one of its more specific subcodes instead.