ICD-10-CM 2027
ICD-10 code for Cryoglobulinemia
From the official ICD-10-CM alphabetic index entry “Cryoglobulinemia (essential) (idiopathic) (mixed) (primary) (purpura) (secondary) (vasculitis)”. Page updated September 29, 2026.
About coding Cryoglobulinemia
The ICD-10-CM code for Cryoglobulinemia is D89.1 (Cryoglobulinemia). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on D89.1.
Within D89 (other disorders involving the immune mechanism, not elsewhere classified), D89.1 is specifically for Cryoglobulinemia. Related codes cover Polyclonal hypergammaglobulinemia (D89.0), hypergammaglobulinemia, unspecified (D89.2), immune reconstitution syndrome (D89.3), mast cell activation syndrome and related disorders (D89.4), other specified disorders involving the immune mechanism, not elsewhere classified (D89.8) and disorder involving the immune mechanism, unspecified (D89.9).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 820 (Lymphoma and Leukemia with Major O.R. Procedures with MCC, relative weight 6.2481), DRG 821 (Lymphoma and Leukemia with Major O.R. Procedures with CC, relative weight 2.2023), DRG 822 (Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC, relative weight 1.1272), DRG 823 (Lymphoma and Non-Acute Leukemia with Other Procedures with MCC, relative weight 4.6059), DRG 824 (Lymphoma and Non-Acute Leukemia with Other Procedures with CC, relative weight 2.2515), DRG 825 (Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC, relative weight 1.2995) and 3 more, in MDC 17 (Myeloproliferative Diseases and Disorders, Poorly Differentiated Neoplasms), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Cryoglobulinemia codes (official index)
- with lung involvement D89.1 — Cryoglobulinemia
Common questions about Cryoglobulinemia ICD-10 codes
What is the ICD-10 code for Cryoglobulinemia?
- D89.1 — Cryoglobulinemia. More specific codes apply when the documentation supports them: D89.1.
Is D89.1 billable?
- Yes. D89.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D89.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D89.1 as a principal diagnosis.
Is D89.1 a CC or MCC?
- No. D89.1 is neither a CC nor an MCC under MS-DRG v44.0.