D89.8Other specified disorders involving the immune mechanism, not elsewhere classified

D89.8 is the ICD-10-CM diagnosis code for other specified disorders involving the immune mechanism, not elsewhere classified. It belongs to category D89 (other disorders involving the immune mechanism, not elsewhere classified), block D80-D89 (certain disorders involving the immune mechanism) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is a header code, so it can't be reported by itself; one of its 5 subcodes must be used instead.

Within D89, choose D89.8 (Other specified disorders involving the immune mechanism, not elsewhere classified) only when documentation doesn't support a more specific option: Polyclonal hypergammaglobulinemia (D89.0), Cryoglobulinemia (D89.1), hypergammaglobulinemia, unspecified (D89.2), immune reconstitution syndrome (D89.3), mast cell activation syndrome and related disorders (D89.4) and disorder involving the immune mechanism, unspecified (D89.9).

To report this condition, pick the subcode that matches the documentation: D89.81 (disease), D89.82 ([ALPS]), D89.83 (syndrome), D89.84 (disease) and D89.89 (classified).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.