ICD-10-CM 2027
ICD-10 code for hepatocellular carcinoma
From the official ICD-10-CM alphabetic index entry “Carcinoma (malignant) › hepatocellular”. Page updated September 29, 2026.
About coding hepatocellular carcinoma
The ICD-10-CM code for hepatocellular carcinoma is C22.0 (Liver cell carcinoma). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on C22.0.
Within C22 (malignant neoplasm of liver and intrahepatic bile ducts), C22.0 is specifically for liver cell carcinoma. Related codes cover intrahepatic bile duct carcinoma (C22.1), Hepatoblastoma (C22.2), Angiosarcoma of liver (C22.3), other sarcomas of liver (C22.4), other specified carcinomas of liver (C22.7), malignant neoplasm of liver, primary, unspecified as to type (C22.8) and malignant neoplasm of liver, not specified as primary or secondary (C22.9).
Use an additional code to identify: alcohol abuse and dependence (F10.-), hepatitis B (B16.-, B18.0-B18.1) and hepatitis C (B17.1-, B18.2).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
More specific hepatocellular carcinoma codes (official index)
Common questions about hepatocellular carcinoma ICD-10 codes
What is the ICD-10 code for hepatocellular carcinoma?
- C22.0 — Liver cell carcinoma. More specific codes apply when the documentation supports them: C22.0, C22.0.
What is the ICD-10 code for fibrolamellar hepatocellular carcinoma?
- C22.0 — Liver cell carcinoma.
Is C22.0 billable?
- Yes. C22.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C22.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C22.0 as a principal diagnosis.
Is C22.0 a CC or MCC?
- C22.0 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.