C22.3Angiosarcoma of liver

C22.3 is the ICD-10-CM diagnosis code for Angiosarcoma of liver. It belongs to category C22 (malignant neoplasm of liver and intrahepatic bile ducts), block C15-C26 (malignant neoplasms of digestive organs) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within C22 (malignant neoplasm of liver and intrahepatic bile ducts), C22.3 is specifically for Angiosarcoma of liver. Related codes cover liver cell carcinoma (C22.0), intrahepatic bile duct carcinoma (C22.1), Hepatoblastoma (C22.2), other sarcomas of liver (C22.4), other specified carcinomas of liver (C22.7), malignant neoplasm of liver, primary, unspecified as to type (C22.8) and malignant neoplasm of liver, not specified as primary or secondary (C22.9).

Use an additional code to identify: alcohol abuse and dependence (F10.-), hepatitis B (B16.-, B18.0-B18.1) and hepatitis C (B17.1-, B18.2).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 435 (Malignancy of Hepatobiliary System or Pancreas with MCC, relative weight 1.843), DRG 436 (Malignancy of Hepatobiliary System or Pancreas with CC, relative weight 1.1224) and DRG 437 (Malignancy of Hepatobiliary System or Pancreas without CC/MCC, relative weight 0.8081), in MDC 07 (Diseases and Disorders of the Hepatobiliary System and Pancreas), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 155.0 (malignant neoplasm of liver, primary).