ICD-10-CM 2027
ICD-10 code for paroxysmal cold hemoglobinuria
From the official ICD-10-CM alphabetic index entry “Hemoglobinuria › paroxysmal (cold)”. Page updated September 29, 2026.
About coding paroxysmal cold hemoglobinuria
The ICD-10-CM code for paroxysmal cold hemoglobinuria is D59.6 (Hemoglobinuria due to hemolysis from other external causes). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on D59.6.
Within D59, choose D59.6 (Hemoglobinuria due to hemolysis from other external causes) only when documentation doesn't support a more specific option: drug-induced autoimmune hemolytic anemia (D59.0), other autoimmune hemolytic anemias (D59.1), drug-induced nonautoimmune hemolytic anemia (D59.2), hemolytic-uremic syndrome (D59.3), other nonautoimmune hemolytic anemias (D59.4), paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli] (D59.5), other acquired hemolytic anemias (D59.8) and unspecified (D59.9).
Don't report D59.6 together with the conditions in its Excludes1 note: hemoglobinuria NOS (R82.3).
Use an additional code (Chapter 20) to identify external cause.
More specific paroxysmal cold hemoglobinuria codes (official index)
- nocturnal D59.5 — Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
Don't confuse with (Excludes1 for D59.6)
- hemoglobinuria NOS (R82.3)
Common questions about paroxysmal cold hemoglobinuria ICD-10 codes
What is the ICD-10 code for paroxysmal cold hemoglobinuria?
- D59.6 — Hemoglobinuria due to hemolysis from other external causes. More specific codes apply when the documentation supports them: D59.5.
What is the ICD-10 code for nocturnal paroxysmal cold hemoglobinuria?
- D59.5 — Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli].
Is D59.6 billable?
- Yes. D59.6 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D59.6 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D59.6 as a principal diagnosis.
Is D59.6 a CC or MCC?
- No. D59.6 is neither a CC nor an MCC under MS-DRG v44.0.