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ICD-10-CM 2027 diagnosis code

D57.04Hb-SS disease with dactylitis

✓ Billable / specificMCC — major complication/comorbidity

D57.04 is a valid, billable ICD-10-CM code for hb-ss disease with dactylitis. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code last changed in FY2024 (effective October 1, 2023). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D57.04

D57.04 is the ICD-10-CM diagnosis code for Hb-SS disease with dactylitis. It belongs to category D57 (sickle-cell disorders), block D55-D59 (hemolytic anemias) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D57.0 (Hb-SS disease with crisis), D57.04 is specifically for Hb-SS disease with dactylitis. Related codes cover unspecified (D57.00), acute chest syndrome (D57.01), splenic sequestration (D57.02), cerebral vascular involvement (D57.03) and with other specified complication (D57.09).

Use an additional code for any associated fever (R50.81).

As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 811 (Red Blood Cell Disorders with MCC, relative weight 1.3988) and DRG 812 (Red Blood Cell Disorders without MCC, relative weight 0.9234), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2024, effective October 1, 2023.

Notes that apply from higher levels

Instructions written at a parent level also apply to D57.04.

› From D57 Sickle-cell disorders
Excludes1
  • other hemoglobinopathies (D58.-)
Use additional code
  • code for any associated fever (R50.81)

Broader instructions also apply from Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.

Alphabetic index entries

5 entries

Terms in the official ICD-10-CM index that lead to D57.04.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 16 · Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2024 (effective 10/1/2023): Added
  • No changes since FY2024.

Common questions about D57.04

Is D57.04 billable?

Yes. D57.04 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D57.04 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D57.04 as a principal diagnosis.

Is D57.04 a CC or MCC?

D57.04 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.

What DRG does D57.04 group to?

D57.04 is used in the MS-DRG v44.0 logic for MS-DRG 811 (Red Blood Cell Disorders with MCC) and MS-DRG 812 (Red Blood Cell Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.