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ICD-10-CM 2027 diagnosis code

E74.31Sucrase-isomaltase deficiency

✓ Billable / specific

E74.31 is a valid, billable ICD-10-CM code for sucrase-isomaltase deficiency. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E74.31

E74.31 is the ICD-10-CM diagnosis code for Sucrase-isomaltase deficiency. It belongs to category E74 (other disorders of carbohydrate metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E74.3 (other disorders of intestinal carbohydrate absorption), E74.31 is specifically for Sucrase-isomaltase deficiency. Related codes cover other disorders of intestinal carbohydrate absorption (E74.39).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC, relative weight 1.2392) and DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC, relative weight 0.7645), in MDC 06 (Diseases and Disorders of the Digestive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 271.3 (intestinal disaccharidase deficiencies and disaccharide malabsorption).

Notes that apply from higher levels

Instructions written at a parent level also apply to E74.31.

› From E74.3 Other disorders of intestinal carbohydrate absorption
Excludes2
  • lactose intolerance (E73.-)
› From E74 Other disorders of carbohydrate metabolism
Excludes1

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

2 entries

Terms in the official ICD-10-CM index that lead to E74.31.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 271.3Intestinal disaccharidase deficiencies and disaccharide malabsorptionapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E74.31

Is E74.31 billable?

Yes. E74.31 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E74.31 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E74.31 as a principal diagnosis.

Is E74.31 a CC or MCC?

No. E74.31 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does E74.31 group to?

E74.31 is used in the MS-DRG v44.0 logic for MS-DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC) and MS-DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for E74.31?

The CMS General Equivalence Mappings map E74.31 to ICD-9-CM 271.3.