ICD-10-CM 2027 diagnosis code
T65.8Toxic effect of other specified substances
T65.8 is a header code, so it can't be reported by itself. Choose one of the 6 more specific codes beneath it and add the required 7th character.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T65.8
T65.8 is the ICD-10-CM diagnosis code for toxic effect of other specified substances. It belongs to category T65 (toxic effect of other and unspecified substances), block T51-T65 (toxic effects of substances chiefly nonmedicinal as to source) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 6 subcodes must be used instead.
Within T65, choose T65.8 (other specified substances) only when documentation doesn't support a more specific option: cyanides (T65.0), strychnine and its salts (T65.1), tobacco and nicotine (T65.2), nitroderivatives and aminoderivatives of benzene and its homologues (T65.3), carbon disulfide (T65.4), nitroglycerin and other nitric acids and esters (T65.5), paints and dyes, not elsewhere classified (T65.6) and unspecified substance (T65.9).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
7th character
The appropriate 7th character is to be added to each code from category T65
- T65.81Toxic effect of latex
- T65.82Toxic effect of harmful algae and algae toxins
- T65.83Toxic effect of fiberglass
- T65.84Toxic effect of xylazine
- T65.85Toxic effect of medetomidine
- T65.89Toxic effect of other specified substances
- Ainitial encounter
- Dsubsequent encounter
- Ssequela
Notes that apply from higher levels
Instructions written at a parent level also apply to T65.8.
Broader instructions also apply from T51-T65 Toxic effects of substances chiefly nonmedicinal as to source and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about T65.8
Is T65.8 billable?
- No. T65.8 is a header code. Report one of its more specific subcodes instead.