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ICD-10-CM 2027 diagnosis code

T65.841Toxic effect of xylazine, accidental (unintentional)

Not billable — use a more specific codeRequires 7th character

T65.841 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it and add the required 7th character.

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About T65.841

T65.841 is the ICD-10-CM diagnosis code for toxic effect of xylazine, accidental (unintentional). It belongs to category T65 (toxic effect of other and unspecified substances), block T51-T65 (toxic effects of substances chiefly nonmedicinal as to source) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within T65.84 (toxic effect of xylazine), T65.841 is specifically for toxic effect of xylazine, accidental (unintentional). Related codes cover intentional self-harm (T65.842), assault (T65.843) and undetermined (T65.844).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

It was added in FY2026, effective October 1, 2025.

7th character

The appropriate 7th character is to be added to each code from category T65

Coding notes

Applicable toConditions and synonyms classified to this code
  • Toxic effect of xylazine NOS

Notes that apply from higher levels

Instructions written at a parent level also apply to T65.841.

› From T65.84 Toxic effect of xylazine
Use additional code
  • code(s) for all associated manifestations, such as:
  • cellulitis and acute lymphangitis (L03.-)
  • cutaneous abscess, furuncle and carbuncle (L02.-)
  • non-pressure chronic ulcer of lower limb, not elsewhere classified (L97.-)
  • non-pressure chronic ulcer of skin, not elsewhere classified (L98.4-)

Broader instructions also apply from T51-T65 Toxic effects of substances chiefly nonmedicinal as to source and Chapter 19: Injury, poisoning and certain other consequences of external causes.

Table of Drugs & Neoplasms entries

  • Xylazine — Poisoning Accidental (unintentional)

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2026 (effective 10/1/2025): Added
  • No changes since FY2026.

Common questions about T65.841

Is T65.841 billable?

No. T65.841 is a header code. Report one of its more specific subcodes instead.