ICD-10-CM 2027 diagnosis code
T65.84Toxic effect of xylazine
T65.84 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it and add the required 7th character.
Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About T65.84
T65.84 is the ICD-10-CM diagnosis code for toxic effect of xylazine. It belongs to category T65 (toxic effect of other and unspecified substances), block T51-T65 (toxic effects of substances chiefly nonmedicinal as to source) and chapter 19 (injury, poisoning and certain other consequences of external causes). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.
Within T65.8 (toxic effect of other specified substances), T65.84 is specifically for toxic effect of xylazine. Related codes cover latex (T65.81), harmful algae and algae toxins (T65.82), fiberglass (T65.83), medetomidine (T65.85) and other specified substances (T65.89).
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
Use an additional code(s) for all associated manifestations, such as: cellulitis and acute lymphangitis (L03.-), cutaneous abscess, furuncle and carbuncle (L02.-), non-pressure chronic ulcer of lower limb, not elsewhere classified (L97.-) and non-pressure chronic ulcer of skin, not elsewhere classified (L98.4-).
It was added in FY2026, effective October 1, 2025.
7th character
The appropriate 7th character is to be added to each code from category T65
- T65.841Toxic effect of xylazine, accidental (unintentional)
- T65.842Toxic effect of xylazine, intentional self-harm
- T65.843Toxic effect of xylazine, assault
- T65.844Toxic effect of xylazine, undetermined
- Ainitial encounter
- Dsubsequent encounter
- Ssequela
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to T65.84.
Broader instructions also apply from T51-T65 Toxic effects of substances chiefly nonmedicinal as to source and Chapter 19: Injury, poisoning and certain other consequences of external causes.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2026 (effective 10/1/2025): Added
- No changes since FY2026.
Common questions about T65.84
Is T65.84 billable?
- No. T65.84 is a header code. Report one of its more specific subcodes instead.