ICD-10-CM 2027
ICD-10 code for degeneration
Choose a code from the options below based on the documentation.
From the official ICD-10-CM alphabetic index entry “Degeneration, degenerative”. Page updated September 29, 2026.
About coding degeneration
The official ICD-10-CM index doesn't give a single default code for degeneration; the code depends on the details below.
More specific degeneration codes (official index)
- adrenal (capsule) (fatty) (gland) (hyaline) (infectional) E27.8 — Other specified disorders of adrenal gland
- amyloid E85.9 — Amyloidosis, unspecified
- anterior cornua, spinal cord G12.29 — Other motor neuron disease
- anterior labral S43.49 — Other sprain of shoulder joint
- aorta, aortic I70.0 — Atherosclerosis of aorta
- fatty I77.89 — Other specified disorders of arteries and arterioles
- aortic valve (heart)
- arteriovascular
- artery, arterial (atheromatous) (calcareous)
- cerebral, amyloid E85.4 — Organ-limited amyloidosis
- medial
- articular cartilage NEC
- atheromatous
- basal nuclei or ganglia G23.9 — Degenerative disease of basal ganglia, unspecified
- specified NEC G23.8 — Other specified degenerative diseases of basal ganglia
- bone NEC
- brachial plexus G54.0 — Brachial plexus disorders
- brain (cortical) (progressive) G31.9 — Degenerative disease of nervous system, unspecified
- alcoholic G31.2 — Degeneration of nervous system due to alcohol
- arteriosclerotic I67.2 — Cerebral atherosclerosis
- childhood G31.9 — Degenerative disease of nervous system, unspecified
- specified NEC G31.89 — Other specified degenerative diseases of nervous system
- cystic G31.89 — Other specified degenerative diseases of nervous system
- congenital Q04.6 — Congenital cerebral cysts
- in
- alcoholism G31.2 — Degeneration of nervous system due to alcohol
- beriberi E51.2 — Wernicke's encephalopathy
- cerebrovascular disease I67.9 — Cerebrovascular disease, unspecified
- congenital hydrocephalus Q03.9 — Congenital hydrocephalus, unspecified
- with spina bifida
- Fabry-Anderson disease E75.21 — Fabry (-Anderson) disease
- Gaucher's disease E75.22 — Gaucher disease
- Hunter's syndrome E76.1 — Mucopolysaccharidosis, type II
- lipidosis
- cerebral E75.4 — Neuronal ceroid lipofuscinosis
- generalized E75.6 — Lipid storage disorder, unspecified
- mucopolysaccharidosis
- myxedema E03.9 — Hypothyroidism, unspecified
- neoplastic disease D49.6 — Neoplasm of unspecified behavior of brain
- Niemann-Pick disease E75.249 — Niemann-Pick disease, unspecified
- sphingolipidosis E75.3 — Sphingolipidosis, unspecified
- vitamin B12 deficiency E53.8 — Deficiency of other specified B group vitamins
- senile NEC G31.1 — Senile degeneration of brain, not elsewhere classified
- breast N64.89 — Other specified disorders of breast
- Bruch's membrane
- capillaries (fatty) I78.8 — Other diseases of capillaries
- amyloid E85.89 — Other amyloidosis
- cardiac
- valve, valvular
- cardiorenal
- cardiovascular
- renal
- cerebellar NOS G31.9 — Degenerative disease of nervous system, unspecified
- alcoholic G31.2 — Degeneration of nervous system due to alcohol
- primary (hereditary) (sporadic) G11.9 — Hereditary ataxia, unspecified
- cerebral
- cerebrovascular I67.9 — Cerebrovascular disease, unspecified
- due to hypertension I67.4 — Hypertensive encephalopathy
- cervical plexus G54.2 — Cervical root disorders, not elsewhere classified
- cervix N88.8 — Other specified noninflammatory disorders of cervix uteri
- due to radiation (intended effect) N88.8 — Other specified noninflammatory disorders of cervix uteri
- adverse effect or misadventure N99.89 — Other postprocedural complications and disorders of genitourinary system
- chamber angle H21.21 — Degeneration of chamber angle
- changes, spine or vertebra
- chorioretinal
- hereditary H31.20 — Hereditary choroidal dystrophy, unspecified
- choroid (colloid) (drusen) H31.10 — Unspecified choroidal degeneration
- atrophy
- hereditary
- ciliary body H21.22 — Degeneration of ciliary body
- cochlear
- combined (spinal cord) (subacute) E53.8 — Deficiency of other specified B group vitamins
- with anemia (pernicious) D51.0 — Vitamin B12 deficiency anemia due to intrinsic factor deficiency
- due to dietary vitamin B12 deficiency D51.3 — Other dietary vitamin B12 deficiency anemia
- in (due to)
- vitamin B12 deficiency E53.8 — Deficiency of other specified B group vitamins
- anemia D51.9 — Vitamin B12 deficiency anemia, unspecified
- conjunctiva H11.10 — Unspecified conjunctival degenerations
- concretions
- deposits
- pigmentations
- pinguecula
- xerosis
- cornea H18.40 — Unspecified corneal degeneration
- calcerous H18.43 — Other calcerous corneal degeneration
- band keratopathy H18.42 — Band keratopathy
- familial, hereditary
- hyaline (of old scars) H18.49 — Other corneal degeneration
- keratomalacia
- nodular H18.45 — Nodular corneal degeneration
- peripheral H18.46 — Peripheral corneal degeneration
- senile H18.41 — Arcus senilis
- specified type NEC H18.49 — Other corneal degeneration
- cortical (cerebellar) (parenchymatous) G31.89 — Other specified degenerative diseases of nervous system
- alcoholic G31.2 — Degeneration of nervous system due to alcohol
- diffuse, due to arteriopathy I67.2 — Cerebral atherosclerosis
- corticobasal G31.85 — Corticobasal degeneration
- cutis L98.8 — Other specified disorders of the skin and subcutaneous tissue
- amyloid E85.4 — Organ-limited amyloidosis
- dental pulp K04.2 — Pulp degeneration
- disc disease
- dorsolateral (spinal cord)
- extrapyramidal G25.9 — Extrapyramidal and movement disorder, unspecified
- eye, macular
- congenital or hereditary
- facet joints
- fatty
- liver NEC K76.0 — Fatty (change of) liver, not elsewhere classified
- alcoholic K70.0 — Alcoholic fatty liver
- grey matter (brain) (Alpers') G31.81 — Alpers disease
- heart
- amyloid E85.4 — Organ-limited amyloidosis
- atheromatous
- ischemic
- hepatolenticular (Wilson's) E83.01 — Wilson's disease
- hepatorenal K76.7 — Hepatorenal syndrome
- hyaline (diffuse) (generalized)
- localized
- infrapatellar fat pad M79.4 — Hypertrophy of (infrapatellar) fat pad
- intervertebral disc
- with
- myelopathy
- radiculitis or radiculopathy
- cervical, cervicothoracic
- with
- myelopathy
- neuritis, radiculitis or radiculopathy
- lumbar region M51.36 — Other intervertebral disc degeneration, lumbar region
- with
- myelopathy M51.06 — Intervertebral disc disorders with myelopathy, lumbar region
- neuritis, radiculitis, radiculopathy or sciatica M51.16 — Intervertebral disc disorders with radiculopathy, lumbar region
- lumbosacral region M51.37 — Other intervertebral disc degeneration, lumbosacral region
- with
- neuritis, radiculitis, radiculopathy or sciatica M51.17 — Intervertebral disc disorders with radiculopathy, lumbosacral region
- sacrococcygeal region M53.3 — Sacrococcygeal disorders, not elsewhere classified
- thoracic region M51.34 — Other intervertebral disc degeneration, thoracic region
- with
- myelopathy M51.04 — Intervertebral disc disorders with myelopathy, thoracic region
- neuritis, radiculitis, radiculopathy M51.14 — Intervertebral disc disorders with radiculopathy, thoracic region
- thoracolumbar region M51.35 — Other intervertebral disc degeneration, thoracolumbar region
- with
- myelopathy M51.05 — Intervertebral disc disorders with myelopathy, thoracolumbar region
- neuritis, radiculitis, radiculopathy M51.15 — Intervertebral disc disorders with radiculopathy, thoracolumbar region
- intestine, amyloid E85.4 — Organ-limited amyloidosis
- iris (pigmentary) H21.23 — Degeneration of iris (pigmentary)
- ischemic
- joint disease
- kidney N28.89 — Other specified disorders of kidney and ureter
- amyloid E85.4 — Organ-limited amyloidosis
- cystic, congenital Q61.9 — Cystic kidney disease, unspecified
- fatty N28.89 — Other specified disorders of kidney and ureter
- polycystic Q61.3 — Polycystic kidney, unspecified
- adult type (autosomal dominant) Q61.2 — Polycystic kidney, adult type
- infantile type (autosomal recessive) NEC Q61.19 — Other polycystic kidney, infantile type
- collecting duct dilatation Q61.11 — Cystic dilatation of collecting ducts
- Kuhnt-Junius H35.32 — Exudative age-related macular degeneration
- lens
- lenticular (familial) (progressive) (Wilson's) (with cirrhosis of liver) E83.01 — Wilson's disease
- liver (diffuse) NEC K76.89 — Other specified diseases of liver
- amyloid E85.4 — Organ-limited amyloidosis
- cystic K76.89 — Other specified diseases of liver
- congenital Q44.6 — Cystic disease of liver
- fatty NEC K76.0 — Fatty (change of) liver, not elsewhere classified
- alcoholic K70.0 — Alcoholic fatty liver
- hypertrophic K76.89 — Other specified diseases of liver
- parenchymatous, acute or subacute K72.00 — Acute and subacute hepatic failure without coma
- with coma K72.01 — Acute and subacute hepatic failure with coma
- pigmentary K76.89 — Other specified diseases of liver
- toxic (acute) K71.9 — Toxic liver disease, unspecified
- lung J98.4 — Other disorders of lung
- lymph gland I89.8 — Other specified noninfective disorders of lymphatic vessels and lymph nodes
- hyaline I89.8 — Other specified noninfective disorders of lymphatic vessels and lymph nodes
- macula, macular (acquired) (age-related) (senile) H35.30 — Unspecified macular degeneration
- angioid streaks H35.33 — Angioid streaks of macula
- atrophic age-related H35.31 — Nonexudative age-related macular degeneration
- congenital or hereditary
- cystoid H35.35 — Cystoid macular degeneration
- drusen H35.36 — Drusen (degenerative) of macula
- dry age-related H35.31 — Nonexudative age-related macular degeneration
- exudative H35.32 — Exudative age-related macular degeneration
- hole H35.34 — Macular cyst, hole, or pseudohole
- nonexudative H35.31 — Nonexudative age-related macular degeneration
- puckering H35.37 — Puckering of macula
- toxic H35.38 — Toxic maculopathy
- wet age-related H35.32 — Exudative age-related macular degeneration
- membranous labyrinth, congenital (causing impairment of hearing) Q16.5 — Congenital malformation of inner ear
- meniscus
- mitral
- Mönckeberg's
- motor centers, senile G31.1 — Senile degeneration of brain, not elsewhere classified
- multi-system G90.3 — Multi-system degeneration of the autonomic nervous system
- mural
- muscle (fatty) (fibrous) (hyaline) (progressive) M62.89 — Other specified disorders of muscle
- heart
- myelin, central nervous system G37.9 — Demyelinating disease of central nervous system, unspecified
- myocardial, myocardium (fatty) (hyaline) (senile) I51.5 — Myocardial degeneration
- with rheumatic fever (conditions in I00) I09.0 — Rheumatic myocarditis
- active, acute or subacute I01.2 — Acute rheumatic myocarditis
- with chorea I02.0 — Rheumatic chorea with heart involvement
- inactive or quiescent (with chorea) I09.0 — Rheumatic myocarditis
- hypertensive
- rheumatic
- syphilitic A52.06 — Other syphilitic heart involvement
- nasal sinus (mucosa) J32.9 — Chronic sinusitis, unspecified
- frontal J32.1 — Chronic frontal sinusitis
- maxillary J32.0 — Chronic maxillary sinusitis
- nerve
- nervous system G31.9 — Degenerative disease of nervous system, unspecified
- alcoholic G31.2 — Degeneration of nervous system due to alcohol
- amyloid E85.4 — Organ-limited amyloidosis
- autonomic G90.9 — Disorder of the autonomic nervous system, unspecified
- fatty G31.89 — Other specified degenerative diseases of nervous system
- specified NEC G31.89 — Other specified degenerative diseases of nervous system
- nipple N64.89 — Other specified disorders of breast
- olivopontocerebellar (hereditary) (familial) G23.8 — Other specified degenerative diseases of basal ganglia
- osseous labyrinth
- ovary N83.8 — Other noninflammatory disorders of ovary, fallopian tube and broad ligament
- cystic N83.20 — Unspecified ovarian cysts
- microcystic N83.20 — Unspecified ovarian cysts
- pallidal pigmentary (progressive) G23.0 — Hallervorden-Spatz disease
- pancreas K86.89 — Other specified diseases of pancreas
- tuberculous A18.83 — Tuberculosis of digestive tract organs, not elsewhere classified
- penis N48.89 — Other specified disorders of penis
- pigmentary (diffuse) (general)
- localized
- pallidal (progressive) G23.0 — Hallervorden-Spatz disease
- pineal gland E34.8 — Other specified endocrine disorders
- pituitary (gland) E23.6 — Other disorders of pituitary gland
- popliteal fat pad M79.4 — Hypertrophy of (infrapatellar) fat pad
- posterolateral (spinal cord)
- pulmonary valve (heart) I37.8 — Other nonrheumatic pulmonary valve disorders
- pulp (tooth) K04.2 — Pulp degeneration
- pupillary margin H21.24 — Degeneration of pupillary margin
- renal
- retina H35.9 — Unspecified retinal disorder
- hereditary (cerebroretinal) (congenital) (juvenile) (macula) (peripheral) (pigmentary)
- Kuhnt-Junius H35.32 — Exudative age-related macular degeneration
- macula (cystic) (exudative) (hole) (nonexudative) (pseudohole) (senile) (toxic)
- peripheral H35.40 — Unspecified peripheral retinal degeneration
- lattice H35.41 — Lattice degeneration of retina
- microcystoid H35.42 — Microcystoid degeneration of retina
- paving stone H35.43 — Paving stone degeneration of retina
- secondary
- pigmentary H35.45 — Secondary pigmentary degeneration
- vitreoretinal H35.46 — Secondary vitreoretinal degeneration
- senile reticular H35.44 — Age-related reticular degeneration of retina
- pigmentary (primary)
- secondary
- posterior pole
- saccule, congenital (causing impairment of hearing) Q16.5 — Congenital malformation of inner ear
- senile R54 — Age-related physical debility
- brain G31.1 — Senile degeneration of brain, not elsewhere classified
- cardiac, heart or myocardium
- motor centers G31.1 — Senile degeneration of brain, not elsewhere classified
- vascular
- sinus (cystic)
- polypoid J33.1 — Polypoid sinus degeneration
- skin L98.8 — Other specified disorders of the skin and subcutaneous tissue
- amyloid E85.4 — Organ-limited amyloidosis
- colloid L98.8 — Other specified disorders of the skin and subcutaneous tissue
- spinal (cord) G31.89 — Other specified degenerative diseases of nervous system
- amyloid E85.4 — Organ-limited amyloidosis
- combined (subacute)
- dorsolateral
- familial NEC G31.89 — Other specified degenerative diseases of nervous system
- fatty G31.89 — Other specified degenerative diseases of nervous system
- funicular
- posterolateral
- subacute combined
- tuberculous A17.81 — Tuberculoma of brain and spinal cord
- spleen D73.0 — Hyposplenism
- amyloid E85.4 — Organ-limited amyloidosis
- stomach K31.89 — Other diseases of stomach and duodenum
- striatonigral G23.2 — Striatonigral degeneration
- suprarenal (capsule) (gland) E27.8 — Other specified disorders of adrenal gland
- synovial membrane (pulpy)
- tapetoretinal
- thymus (gland) E32.8 — Other diseases of thymus
- fatty E32.8 — Other diseases of thymus
- thyroid (gland) E07.89 — Other specified disorders of thyroid
- tricuspid (heart) (valve) I07.9 — Rheumatic tricuspid valve disease, unspecified
- tuberculous NEC
- turbinate J34.89 — Other specified disorders of nose and nasal sinuses
- uterus (cystic) N85.8 — Other specified noninflammatory disorders of uterus
- vascular (senile)
- hypertensive
- vitreoretinal, secondary
- vitreous (body) H43.81 — Vitreous degeneration
- Wallerian
- Wilson's hepatolenticular E83.01 — Wilson's disease
Common questions about degeneration ICD-10 codes
What is the ICD-10 code for adrenal degeneration?
- E27.8 — Other specified disorders of adrenal gland.
What is the ICD-10 code for amyloid degeneration?
- E85.9 — Amyloidosis, unspecified.
What is the ICD-10 code for anterior labral degeneration?
- S43.49 — Other sprain of shoulder joint (header code; choose a more specific subcode).
What is the ICD-10 code for basal nuclei or ganglia degeneration?
- G23.9 — Degenerative disease of basal ganglia, unspecified.
What is the ICD-10 code for brachial plexus degeneration?
- G54.0 — Brachial plexus disorders.
What is the ICD-10 code for brain degeneration?
- G31.9 — Degenerative disease of nervous system, unspecified.
What is the ICD-10 code for breast degeneration?
- N64.89 — Other specified disorders of breast.