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ICD-10-CM 2027

ICD-10 code for Franklin disease

C88.2

Heavy chain disease

Header — needs a more specific code

From the official ICD-10-CM alphabetic index entry “Disease, diseased › Franklin”. Page updated September 29, 2026.

About coding Franklin disease

The ICD-10-CM code for Franklin disease is C88.2 (Heavy chain disease).

Within C88 (malignant immunoproliferative diseases and certain other B-cell lymphomas), C88.2 is specifically for heavy chain disease. Related codes cover Waldenstrom macroglobulinemia (C88.0), immunoproliferative small intestinal disease (C88.3), extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] (C88.4), other malignant immunoproliferative diseases (C88.8) and malignant immunoproliferative disease, unspecified (C88.9).

To report this condition, pick the subcode that matches the documentation: C88.20 (not having achieved remission) and C88.21 (in remission).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2025 (expanded into subcodes).

Common questions about Franklin disease ICD-10 codes

What is the ICD-10 code for Franklin disease?

C88.2 — Heavy chain disease (a header code; report a more specific subcode).

Is C88.2 billable?

No. C88.2 is a header code. Report one of its more specific subcodes instead.