Skip to content
Dx

ICD-10-CM 2027

ICD-10 code for Mediterranean lymphoma

C88.3

Immunoproliferative small intestinal disease

Header — needs a more specific code

From the official ICD-10-CM alphabetic index entry “Lymphoma (of) (malignant) › Mediterranean”. Page updated September 29, 2026.

About coding Mediterranean lymphoma

The ICD-10-CM code for Mediterranean lymphoma is C88.3 (Immunoproliferative small intestinal disease).

Within C88 (malignant immunoproliferative diseases and certain other B-cell lymphomas), C88.3 is specifically for immunoproliferative small intestinal disease. Related codes cover Waldenstrom macroglobulinemia (C88.0), heavy chain disease (C88.2), extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] (C88.4), other malignant immunoproliferative diseases (C88.8) and malignant immunoproliferative disease, unspecified (C88.9).

To report this condition, pick the subcode that matches the documentation: C88.30 (not having achieved remission) and C88.31 (in remission).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2025 (expanded into subcodes).

Common questions about Mediterranean lymphoma ICD-10 codes

What is the ICD-10 code for Mediterranean lymphoma?

C88.3 — Immunoproliferative small intestinal disease (a header code; report a more specific subcode).

Is C88.3 billable?

No. C88.3 is a header code. Report one of its more specific subcodes instead.