ICD-10-CM 2027
ICD-10 code for primary hypoadrenocorticism
From the official ICD-10-CM alphabetic index entry “Hypoadrenocorticism › primary”. Page updated September 29, 2026.
About coding primary hypoadrenocorticism
The ICD-10-CM code for primary hypoadrenocorticism is E27.1 (Primary adrenocortical insufficiency).
Within E27 (other disorders of adrenal gland), E27.1 is specifically for primary adrenocortical insufficiency. Related codes cover other adrenocortical overactivity (E27.0), Addisonian crisis (E27.2), drug-induced adrenocortical insufficiency (E27.3), other and unspecified adrenocortical insufficiency (E27.4), Adrenomedullary hyperfunction (E27.5), other specified disorders of adrenal gland (E27.8) and disorder of adrenal gland, unspecified (E27.9).
Don't report E27.1 together with the conditions in its Excludes1 note: Addison only phenotype adrenoleukodystrophy (E71.528), amyloidosis (E85.-), tuberculous Addison's disease (A18.7) and Waterhouse-Friderichsen syndrome (A39.1).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
Don't confuse with (Excludes1 for E27.1)
Common questions about primary hypoadrenocorticism ICD-10 codes
What is the ICD-10 code for primary hypoadrenocorticism?
- E27.1 — Primary adrenocortical insufficiency.
Is E27.1 billable?
- Yes. E27.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E27.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E27.1 as a principal diagnosis.
Is E27.1 a CC or MCC?
- E27.1 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.