ICD-10-CM 2027
ICD-10 code for trait sicklemia
From the official ICD-10-CM alphabetic index entry “Sicklemia › trait”. Page updated September 29, 2026.
About coding trait sicklemia
The ICD-10-CM code for trait sicklemia is D57.3 (Sickle-cell trait).
Within D57 (sickle-cell disorders), D57.3 is specifically for sickle-cell trait. Related codes cover Hb-SS disease with crisis (D57.0), sickle-cell disease without crisis (D57.1), Sickle-cell/Hb-C disease (D57.2), sickle-cell thalassemia (D57.4) and other sickle-cell disorders (D57.8).
Use an additional code for any associated fever (R50.81).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Common questions about trait sicklemia ICD-10 codes
What is the ICD-10 code for trait sicklemia?
- D57.3 — Sickle-cell trait.
Is D57.3 billable?
- Yes. D57.3 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D57.3 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D57.3 as a principal diagnosis.
Is D57.3 a CC or MCC?
- No. D57.3 is neither a CC nor an MCC under MS-DRG v44.0.