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ICD-10-CM 2027 diagnosis code

C49.AGastrointestinal stromal tumor

Not billable — use a more specific code

C49.A is a header code, so it can't be reported by itself. Choose one of the 7 more specific codes beneath it.

Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About C49.A

C49.A is the ICD-10-CM diagnosis code for gastrointestinal stromal tumor. It belongs to category C49 (malignant neoplasm of other connective and soft tissue), block C45-C49 (malignant neoplasms of mesothelial and soft tissue) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 7 subcodes must be used instead.

Within C49 (malignant neoplasm of other connective and soft tissue), C49.A is specifically for gastrointestinal stromal tumor. Related codes cover malignant neoplasm of connective and soft tissue of head, face and neck (C49.0), malignant neoplasm of connective and soft tissue of upper limb, including shoulder (C49.1), malignant neoplasm of connective and soft tissue of lower limb, including hip (C49.2), malignant neoplasm of connective and soft tissue of thorax (C49.3), malignant neoplasm of connective and soft tissue of abdomen (C49.4), malignant neoplasm of connective and soft tissue of pelvis (C49.5), malignant neoplasm of connective and soft tissue of trunk, unspecified (C49.6), malignant neoplasm of overlapping sites of connective and soft tissue (C49.8) and 1 more.

To report this condition, pick the subcode that matches the documentation: C49.A0 (unspecified site), C49.A1 (of esophagus), C49.A2 (of stomach), C49.A3 (of small intestine), C49.A4 (of large intestine), C49.A5 (of rectum) and C49.A9 (of other sites).

It was added in FY2017, effective October 1, 2016.

Specific codes under C49.A

Notes that apply from higher levels

Instructions written at a parent level also apply to C49.A.

› From C49 Malignant neoplasm of other connective and soft tissue
Includes
  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)
Excludes1
  • malignant neoplasm of cartilage (of):
  • articular (C40-C41)
  • larynx (C32.3)
  • nose (C30.0)
  • malignant neoplasm of connective tissue of breast (C50.-)
Excludes2
  • Kaposi's sarcoma of soft tissue (C46.1)
  • malignant neoplasm of heart (C38.0)
  • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
  • malignant neoplasm of peritoneum (C48.2)
  • malignant neoplasm of retroperitoneum (C48.0)
  • malignant neoplasm of uterine ligament (C57.3)
  • mesothelioma (C45.-)

Broader instructions also apply from Chapter 2: Neoplasms.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to C49.A.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2017 (effective 10/1/2016): Added
  • No changes since FY2017.

Common questions about C49.A

Is C49.A billable?

No. C49.A is a header code. Report one of its more specific subcodes instead.