ICD-10-CM 2027 diagnosis code
D43Neoplasm of uncertain behavior of brain and central nervous system
D43 is a header code, so it can't be reported by itself. Choose one of the 7 more specific codes beneath it.Short description: Neoplasm of uncertain behavior of brain and cnsl
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About D43
D43 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of brain and central nervous system. It belongs to block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 7 subcodes must be used instead.
To report this condition, pick the subcode that matches the documentation: D43.0 (supratentorial), D43.1 (infratentorial), D43.2 (unspecified), D43.3 (nerves), D43.4 (cord), D43.8 (system) and D43.9 (unspecified).
Don't report D43 together with the conditions in its Excludes1 note: neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under D43
- D43.0Neoplasm of uncertain behavior of brain, supratentorialBillable
- D43.1Neoplasm of uncertain behavior of brain, infratentorialBillable
- D43.2Neoplasm of uncertain behavior of brain, unspecifiedBillable
- D43.3Neoplasm of uncertain behavior of cranial nervesBillable
- D43.4Neoplasm of uncertain behavior of spinal cordBillable
- D43.8Neoplasm of uncertain behavior of other specified parts of central nervous systemBillable
- D43.9Neoplasm of uncertain behavior of central nervous system, unspecifiedBillable
Coding notes
- neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2)
Notes that apply from higher levels
Instructions written at a parent level also apply to D43.
Broader instructions also apply from D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes and Chapter 2: Neoplasms.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about D43
Is D43 billable?
- No. D43 is a header code. Report one of its more specific subcodes instead.