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ICD-10-CM 2027 diagnosis code

D43Neoplasm of uncertain behavior of brain and central nervous system

Not billable — use a more specific code

D43 is a header code, so it can't be reported by itself. Choose one of the 7 more specific codes beneath it.Short description: Neoplasm of uncertain behavior of brain and cnsl

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D43

D43 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of brain and central nervous system. It belongs to block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 7 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: D43.0 (supratentorial), D43.1 (infratentorial), D43.2 (unspecified), D43.3 (nerves), D43.4 (cord), D43.8 (system) and D43.9 (unspecified).

Don't report D43 together with the conditions in its Excludes1 note: neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under D43

Coding notes

Excludes1Not coded here — never report together with this code
  • neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2)

Notes that apply from higher levels

Instructions written at a parent level also apply to D43.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about D43

Is D43 billable?

No. D43 is a header code. Report one of its more specific subcodes instead.