ICD-10-CM 2027 diagnosis code
D43.0Neoplasm of uncertain behavior of brain, supratentorial
D43.0 is a valid, billable ICD-10-CM code for neoplasm of uncertain behavior of brain, supratentorial. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About D43.0
D43.0 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of brain, supratentorial. It belongs to category D43 (neoplasm of uncertain behavior of brain and central nervous system), block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within D43 (neoplasm of uncertain behavior of brain and central nervous system), D43.0 is specifically for neoplasm of uncertain behavior of brain, supratentorial. Related codes cover brain, infratentorial (D43.1), brain, unspecified (D43.2), cranial nerves (D43.3), spinal cord (D43.4), other specified parts of central nervous system (D43.8) and central nervous system, unspecified (D43.9).
Don't report D43.0 together with the conditions in its Excludes1 note: neoplasm of uncertain behavior of fourth ventricle (D43.1).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 054 (Nervous System Neoplasms with MCC, relative weight 1.5194) and DRG 055 (Nervous System Neoplasms without MCC, relative weight 1.0296), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 237.5 (neoplasm of uncertain behavior of brain and spinal cord).
Coding notes
- Neoplasm of uncertain behavior of cerebral ventricle
- Neoplasm of uncertain behavior of cerebrum
- Neoplasm of uncertain behavior of frontal lobe
- Neoplasm of uncertain behavior of occipital lobe
- Neoplasm of uncertain behavior of parietal lobe
- Neoplasm of uncertain behavior of temporal lobe
- neoplasm of uncertain behavior of fourth ventricle (D43.1)
Notes that apply from higher levels
Instructions written at a parent level also apply to D43.0.
› From D43 Neoplasm of uncertain behavior of brain and central nervous system
- neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2)
Broader instructions also apply from D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes and Chapter 2: Neoplasms.
Table of Drugs & Neoplasms entries
- Neoplasm, neoplastic › basal ganglia — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › basal ganglia — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › cerebrum — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › corpus striatum — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › cortex (cerebral) — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › frontal lobe — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › globus pallidus — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › hippocampus — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › hypothalamus — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › internal capsule — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › occipital lobe — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › parietal lobe — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › temporal lobe — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › thalamus — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › uncus — Uncertain Behavior
- Neoplasm, neoplastic › brain NEC › ventricle (floor) — Uncertain Behavior
- Neoplasm, neoplastic › cerebrum, cerebral (cortex) (hemisphere) (white matter) — Uncertain Behavior
- Neoplasm, neoplastic › cerebrum, cerebral (cortex) (hemisphere) (white matter) › ventricle — Uncertain Behavior
- Neoplasm, neoplastic › choroid › plexus — Uncertain Behavior
- Neoplasm, neoplastic › corpus › striatum, cerebrum — Uncertain Behavior
- Neoplasm, neoplastic › cortex › cerebral — Uncertain Behavior
- Neoplasm, neoplastic › ependyma (brain) — Uncertain Behavior
- Neoplasm, neoplastic › frontal › lobe, brain — Uncertain Behavior
- Neoplasm, neoplastic › frontal › pole — Uncertain Behavior
- Neoplasm, neoplastic › ganglia › basal — Uncertain Behavior
- Neoplasm, neoplastic › globus pallidus — Uncertain Behavior
- Neoplasm, neoplastic › hemisphere, cerebral — Uncertain Behavior
- Neoplasm, neoplastic › hippocampus, brain — Uncertain Behavior
- Neoplasm, neoplastic › hypothalamus — Uncertain Behavior
- Neoplasm, neoplastic › insula — Uncertain Behavior
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 01 · Diseases and Disorders of the Nervous System
ICD-9-CM equivalent
Converter →- 237.5Neoplasm of uncertain behavior of brain and spinal cordapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about D43.0
Is D43.0 billable?
- Yes. D43.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D43.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D43.0 as a principal diagnosis.
Is D43.0 a CC or MCC?
- No. D43.0 is neither a CC nor an MCC under MS-DRG v44.0.
What DRG does D43.0 group to?
- D43.0 is used in the MS-DRG v44.0 logic for MS-DRG 054 (Nervous System Neoplasms with MCC) and MS-DRG 055 (Nervous System Neoplasms without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for D43.0?
- The CMS General Equivalence Mappings map D43.0 to ICD-9-CM 237.5.