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ICD-10-CM 2027 diagnosis code

D43.2Neoplasm of uncertain behavior of brain, unspecified

✓ Billable / specific

D43.2 is a valid, billable ICD-10-CM code for neoplasm of uncertain behavior of brain, unspecified. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.

Looking up by condition? See ICD-10 code for Subependymal glioma, ICD-10 code for Papillary ependymoma, ICD-10 code for Subependymal astrocytoma, ICD-10 code for Myxopapillary ependymoma.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D43.2

D43.2 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of brain, unspecified. It belongs to category D43 (neoplasm of uncertain behavior of brain and central nervous system), block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D43, choose D43.2 (brain, unspecified) only when documentation doesn't support a more specific option: brain, supratentorial (D43.0), brain, infratentorial (D43.1), cranial nerves (D43.3), spinal cord (D43.4), other specified parts of central nervous system (D43.8) and central nervous system, unspecified (D43.9).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 054 (Nervous System Neoplasms with MCC, relative weight 1.5194) and DRG 055 (Nervous System Neoplasms without MCC, relative weight 1.0296), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 237.5 (neoplasm of uncertain behavior of brain and spinal cord).

Notes that apply from higher levels

Instructions written at a parent level also apply to D43.2.

› From D43 Neoplasm of uncertain behavior of brain and central nervous system
Excludes1
  • neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2)

Broader instructions also apply from D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes and Chapter 2: Neoplasms.

Alphabetic index entries

10 entries

Terms in the official ICD-10-CM index that lead to D43.2.

Table of Drugs & Neoplasms entries

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

ICD-9-CM equivalent

Converter →
  • 237.5Neoplasm of uncertain behavior of brain and spinal cordapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about D43.2

Is D43.2 billable?

Yes. D43.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D43.2 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D43.2 as a principal diagnosis.

Is D43.2 a CC or MCC?

No. D43.2 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does D43.2 group to?

D43.2 is used in the MS-DRG v44.0 logic for MS-DRG 054 (Nervous System Neoplasms with MCC) and MS-DRG 055 (Nervous System Neoplasms without MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.

What is the ICD-9 code for D43.2?

The CMS General Equivalence Mappings map D43.2 to ICD-9-CM 237.5.