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ICD-10-CM 2027 diagnosis code

D46.2Refractory anemia with excess of blasts [RAEB]

Not billable — use a more specific code

D46.2 is a header code, so it can't be reported by itself. Choose one of the 3 more specific codes beneath it.

Looking up by condition? See ICD-10 code for RAEB.

Code last changed in FY2017 (effective October 1, 2016). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D46.2

D46.2 is the ICD-10-CM diagnosis code for refractory anemia with excess of blasts [RAEB]. It belongs to category D46 (myelodysplastic syndromes), block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is a header code, so it can't be reported by itself; one of its 3 subcodes must be used instead.

Within D46 (myelodysplastic syndromes), D46.2 is specifically for refractory anemia with excess of blasts [RAEB]. Related codes cover refractory anemia without ring sideroblasts, so stated (D46.0), refractory anemia with ring sideroblasts (D46.1), refractory anemia, unspecified (D46.4), myelodysplastic syndrome, unspecified (D46.9), refractory cytopenia with multilineage dysplasia (D46.A), refractory cytopenia with multilineage dysplasia and ring sideroblasts (D46.B), myelodysplastic syndrome with isolated del(5q) chromosomal abnormality (D46.C) and other myelodysplastic syndromes (D46.Z).

To report this condition, pick the subcode that matches the documentation: D46.20 (unspecified), D46.21 (1) and D46.22 (2).

Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2017 (title revised).

Specific codes under D46.2

Notes that apply from higher levels

Instructions written at a parent level also apply to D46.2.

› From D46 Myelodysplastic syndromes
Excludes2
  • drug-induced aplastic anemia (D61.1)
Use additional code
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Broader instructions also apply from D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes and Chapter 2: Neoplasms.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to D46.2.

Codes whose notes reference D46.2

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • FY2017 (effective 10/1/2016): Title revised — was “Refractory anemia with excess of blasts”

Common questions about D46.2

Is D46.2 billable?

No. D46.2 is a header code. Report one of its more specific subcodes instead.