ICD-10-CM 2027 diagnosis code

D82Immunodeficiency associated with other major defects

Not billable — use a more specific code

D82 is a header code, so it can't be reported by itself. Choose one of the 7 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D82

D82 is the ICD-10-CM diagnosis code for immunodeficiency associated with other major defects. It belongs to block D80-D89 (certain disorders involving the immune mechanism) and chapter 3 (diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism). It is a header code, so it can't be reported by itself; one of its 7 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: D82.0 (syndrome), D82.1 (syndrome), D82.2 (stature), D82.3 (virus), D82.4 (syndrome), D82.8 (defects) and D82.9 (unspecified).

Don't report D82 together with the conditions in its Excludes1 note: ataxia telangiectasia [Louis-Bar] (G11.3).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under D82

Coding notes

Excludes1Not coded here — never report together with this code

ataxia telangiectasia [Louis-Bar] (G11.3)

Notes that apply from higher levels

Instructions written at a parent level also apply to D82.

Broader instructions also apply from D80-D89 Certain disorders involving the immune mechanism and Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism.

Code history

2016
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2021
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2023
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2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about D82

Is D82 billable?: No. D82 is a header code. Report one of its more specific subcodes instead.