ICD-10-CM 2027 diagnosis code
E23.2Diabetes insipidus
E23.2 is a valid, billable ICD-10-CM code for diabetes insipidus. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.
Looking up by condition? See ICD-10 code for Insipidus diabetes.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E23.2
E23.2 is the ICD-10-CM diagnosis code for diabetes insipidus. It belongs to category E23 (hypofunction and other disorders of the pituitary gland), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.
Within E23 (hypofunction and other disorders of the pituitary gland), E23.2 is specifically for diabetes insipidus. Related codes cover hypopituitarism (E23.0), drug-induced hypopituitarism (E23.1), hypothalamic dysfunction, not elsewhere classified (E23.3), other disorders of pituitary gland (E23.6) and disorder of pituitary gland, unspecified (E23.7).
Don't report E23.2 together with the conditions in its Excludes1 note: nephrogenic diabetes insipidus (N25.1).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 643 (Endocrine Disorders with MCC, relative weight 1.6139), DRG 644 (Endocrine Disorders with CC, relative weight 1.0044), DRG 645 (Endocrine Disorders without CC/MCC, relative weight 0.7459), DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders) and MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Before ICD-10, this condition was coded in ICD-9-CM as 253.5 (diabetes insipidus).
Coding notes
- nephrogenic diabetes insipidus (N25.1)
Notes that apply from higher levels
Instructions written at a parent level also apply to E23.2.
Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.
Alphabetic index entries
8 entriesTerms in the official ICD-10-CM index that lead to E23.2.
- Deficiency, deficient › antidiuretic hormone
- Deficiency, deficient › vasopressin
- Diabetes, diabetic (mellitus) (sugar) › insipidus
- Diabetes, diabetic (mellitus) (sugar) › insipidus › pituitary
- Hyposecretion › antidiuretic hormone
- Hyposecretion › vasopressin
- Inappropriate › secretion › antidiuretic hormone (ADH) (excessive) › deficiency
- Perversion, perverted › function › pituitary gland
Codes whose notes reference E23.2
MS-DRG v44.0 grouping
All DRGs →Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.
MDC 10 · Endocrine, Nutritional and Metabolic Diseases and Disorders
MDC 15 · Newborns and Other Neonates with Conditions Originating in the Perinatal Period
MDC 15 · Newborns and Other Neonates with Conditions Originating in the Perinatal Period
ICD-9-CM equivalent
Converter →- 253.5Diabetes insipidusexact
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E23.2
Is E23.2 billable?
- Yes. E23.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E23.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E23.2 as a principal diagnosis.
Is E23.2 a CC or MCC?
- E23.2 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.
What DRG does E23.2 group to?
- E23.2 is used in the MS-DRG v44.0 logic for MS-DRG 643 (Endocrine Disorders with MCC), MS-DRG 644 (Endocrine Disorders with CC), MS-DRG 645 (Endocrine Disorders without CC/MCC), MS-DRG 791 (Prematurity with Major Problems) and MS-DRG 793 (Full Term Neonate with Major Problems). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.
What is the ICD-9 code for E23.2?
- The CMS General Equivalence Mappings map E23.2 to ICD-9-CM 253.5.