ICD-10-CM 2027 diagnosis code

E31Polyglandular dysfunction

Not billable — use a more specific code

E31 is a header code, so it can't be reported by itself. Choose one of the 5 more specific codes beneath it.

Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS, effective October 1, 2026. Updated September 29, 2026. About our data

About E31

E31 is the ICD-10-CM diagnosis code for polyglandular dysfunction. It belongs to block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 5 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: E31.0 (failure), E31.1 (hyperfunction), E31.2 (syndromes), E31.8 (dysfunction) and E31.9 (unspecified).

Don't report E31 together with the conditions in its Excludes1 note: ataxia telangiectasia [Louis-Bar] (G11.3), dystrophia myotonica [Steinert] (G71.11) and pseudohypoparathyroidism (E20.1).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E31

Coding notes

Excludes1Not coded here — never report together with this code

ataxia telangiectasia [Louis-Bar] (G11.3)
dystrophia myotonica [Steinert] (G71.11)
pseudohypoparathyroidism (E20.1)

Notes that apply from higher levels

Instructions written at a parent level also apply to E31.

Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about E31

Is E31 billable?: No. E31 is a header code. Report one of its more specific subcodes instead.