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ICD-10-CM 2027 diagnosis code

E31.2Multiple endocrine neoplasia [MEN] syndromes

Not billable — use a more specific code

E31.2 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E31.2

E31.2 is the ICD-10-CM diagnosis code for multiple endocrine neoplasia [MEN] syndromes. It belongs to category E31 (polyglandular dysfunction), block E20-E35 (disorders of other endocrine glands) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

Within E31 (polyglandular dysfunction), E31.2 is specifically for multiple endocrine neoplasia [MEN] syndromes. Related codes cover autoimmune polyglandular failure (E31.0), polyglandular hyperfunction (E31.1), other polyglandular dysfunction (E31.8) and unspecified (E31.9).

To report this condition, pick the subcode that matches the documentation: E31.20 (unspecified), E31.21 (I), E31.22 (IIA) and E31.23 (IIB).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E31.2

Coding notes

Applicable toConditions and synonyms classified to this code
  • Multiple endocrine adenomatosis
Code alsoTwo codes may be needed; sequencing depends on circumstances
  • any associated malignancies and other conditions associated with the syndromes

Notes that apply from higher levels

Instructions written at a parent level also apply to E31.2.

› From E31 Polyglandular dysfunction
Excludes1
  • ataxia telangiectasia [Louis-Bar] (G11.3)
  • dystrophia myotonica [Steinert] (G71.11)
  • pseudohypoparathyroidism (E20.1)

Broader instructions also apply from E20-E35 Disorders of other endocrine glands and Chapter 4: Endocrine, nutritional and metabolic diseases.

Codes whose notes reference E31.2

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E31.2

Is E31.2 billable?

No. E31.2 is a header code. Report one of its more specific subcodes instead.