ICD-10-CM 2027 diagnosis code

E71.54Other peroxisomal disorders

Not billable — use a more specific code

E71.54 is a header code, so it can't be reported by itself. Choose one of the 4 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E71.54

E71.54 is the ICD-10-CM diagnosis code for other peroxisomal disorders. It belongs to category E71 (disorders of branched-chain amino-acid metabolism and fatty-acid metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 4 subcodes must be used instead.

Within E71.5, choose E71.54 (Other peroxisomal disorders) only when documentation doesn't support a more specific option: peroxisomal disorder, unspecified (E71.50), disorders of peroxisome biogenesis (E71.51), X-linked adrenoleukodystrophy (E71.52) and other group 2 peroxisomal disorders (E71.53).

To report this condition, pick the subcode that matches the documentation: E71.540 (punctata), E71.541 (syndrome), E71.542 (disorders) and E71.548 (disorders).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E71.54

Notes that apply from higher levels

Instructions written at a parent level also apply to E71.54.

› From E71.5 Peroxisomal disorders

Excludes1

Schilder's disease (G37.0)

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Code history

2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027

FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
No changes since FY2016.

Common questions about E71.54

Is E71.54 billable?: No. E71.54 is a header code. Report one of its more specific subcodes instead.