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ICD-10-CM 2027

ICD-10 code for hypopituitarism

E23.0

Hypopituitarism

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Hypopituitarism (juvenile)”. Page updated September 29, 2026.

About coding hypopituitarism

The ICD-10-CM code for hypopituitarism is E23.0 (Hypopituitarism). The official index lists 7 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E23.0.

Within E23 (hypofunction and other disorders of the pituitary gland), E23.0 is specifically for hypopituitarism. Related codes cover drug-induced hypopituitarism (E23.1), diabetes insipidus (E23.2), hypothalamic dysfunction, not elsewhere classified (E23.3), other disorders of pituitary gland (E23.6) and disorder of pituitary gland, unspecified (E23.7).

Use an additional code, if applicable, for associated cachexia (E88.A).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

More specific hypopituitarism codes (official index)

  • drug-induced E23.1 — Drug-induced hypopituitarism
  • due to
  • hypophysectomy E89.3 — Postprocedural hypopituitarism
  • radiotherapy E89.3 — Postprocedural hypopituitarism
  • iatrogenic NEC E23.1 — Drug-induced hypopituitarism
  • postirradiation E89.3 — Postprocedural hypopituitarism
  • postpartum O99.285 — Endocrine, nutritional and metabolic diseases complicating the puerperium
  • postprocedural E89.3 — Postprocedural hypopituitarism

Common questions about hypopituitarism ICD-10 codes

What is the ICD-10 code for hypopituitarism?

E23.0 — Hypopituitarism. More specific codes apply when the documentation supports them: E23.1, E89.3, E89.3, E23.1 and others below.

What is the ICD-10 code for drug-induced hypopituitarism?

E23.1 — Drug-induced hypopituitarism.

What is the ICD-10 code for iatrogenic nec hypopituitarism?

E23.1 — Drug-induced hypopituitarism.

What is the ICD-10 code for postirradiation hypopituitarism?

E89.3 — Postprocedural hypopituitarism.

What is the ICD-10 code for postpartum hypopituitarism?

O99.285 — Endocrine, nutritional and metabolic diseases complicating the puerperium.

What is the ICD-10 code for postprocedural hypopituitarism?

E89.3 — Postprocedural hypopituitarism.

Is E23.0 billable?

Yes. E23.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E23.0 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E23.0 as a principal diagnosis.

Is E23.0 a CC or MCC?

E23.0 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.