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ICD-10-CM 2027

ICD-10 code for primary hyperoxaluria

E72.53

Primary hyperoxaluria

Header — needs a more specific code

From the official ICD-10-CM alphabetic index entry “Hyperoxaluria › primary”. Page updated September 29, 2026.

About coding primary hyperoxaluria

The ICD-10-CM code for primary hyperoxaluria is E72.53 (Primary hyperoxaluria).

Within E72.5 (disorders of glycine metabolism), E72.53 is specifically for primary hyperoxaluria. Related codes cover disorder of glycine metabolism, unspecified (E72.50), Non-ketotic hyperglycinemia (E72.51), Trimethylaminuria (E72.52), secondary hyperoxaluria (E72.54) and other disorders of glycine metabolism (E72.59).

To report this condition, pick the subcode that matches the documentation: E72.530 (type 1), E72.538 (hyperoxaluria) and E72.539 (unspecified).

Don't report E72.53 together with the conditions in its Excludes1 note: secondary hyperoxaluria (E72.54-).

Don't confuse with (Excludes1 for E72.53)

Common questions about primary hyperoxaluria ICD-10 codes

What is the ICD-10 code for primary hyperoxaluria?

E72.53 — Primary hyperoxaluria (a header code; report a more specific subcode).

Is E72.53 billable?

No. E72.53 is a header code. Report one of its more specific subcodes instead.