ICD-10-CM 2027 diagnosis code
E72.5Disorders of glycine metabolism
E72.5 is a header code, so it can't be reported by itself. Choose one of the 6 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E72.5
E72.5 is the ICD-10-CM diagnosis code for disorders of glycine metabolism. It belongs to category E72 (other disorders of amino-acid metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 6 subcodes must be used instead.
Within E72 (other disorders of amino-acid metabolism), E72.5 is specifically for disorders of glycine metabolism. Related codes cover disorders of amino-acid transport (E72.0), disorders of sulfur-bearing amino-acid metabolism (E72.1), disorders of urea cycle metabolism (E72.2), disorders of lysine and hydroxylysine metabolism (E72.3), disorders of ornithine metabolism (E72.4), other specified disorders of amino-acid metabolism (E72.8) and disorder of amino-acid metabolism, unspecified (E72.9).
To report this condition, pick the subcode that matches the documentation: E72.50 (unspecified), E72.51 (hyperglycinemia), E72.52 (Trimethylaminuria), E72.53 (hyperoxaluria), E72.54 (hyperoxaluria) and E72.59 (metabolism).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under E72.5
Notes that apply from higher levels
Instructions written at a parent level also apply to E72.5.
Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E72.5
Is E72.5 billable?
- No. E72.5 is a header code. Report one of its more specific subcodes instead.