Skip to content
Dx

ICD-10-CM 2027 diagnosis code

E72.5Disorders of glycine metabolism

Not billable — use a more specific code

E72.5 is a header code, so it can't be reported by itself. Choose one of the 6 more specific codes beneath it.

Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E72.5

E72.5 is the ICD-10-CM diagnosis code for disorders of glycine metabolism. It belongs to category E72 (other disorders of amino-acid metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 6 subcodes must be used instead.

Within E72 (other disorders of amino-acid metabolism), E72.5 is specifically for disorders of glycine metabolism. Related codes cover disorders of amino-acid transport (E72.0), disorders of sulfur-bearing amino-acid metabolism (E72.1), disorders of urea cycle metabolism (E72.2), disorders of lysine and hydroxylysine metabolism (E72.3), disorders of ornithine metabolism (E72.4), other specified disorders of amino-acid metabolism (E72.8) and disorder of amino-acid metabolism, unspecified (E72.9).

To report this condition, pick the subcode that matches the documentation: E72.50 (unspecified), E72.51 (hyperglycinemia), E72.52 (Trimethylaminuria), E72.53 (hyperoxaluria), E72.54 (hyperoxaluria) and E72.59 (metabolism).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E72.5

Notes that apply from higher levels

Instructions written at a parent level also apply to E72.5.

› From E72 Other disorders of amino-acid metabolism
Excludes1
  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E72.5

Is E72.5 billable?

No. E72.5 is a header code. Report one of its more specific subcodes instead.