E77.1Defects in glycoprotein degradation

E77.1 is the ICD-10-CM diagnosis code for defects in glycoprotein degradation. It belongs to category E77 (disorders of glycoprotein metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E77 (disorders of glycoprotein metabolism), E77.1 is specifically for defects in glycoprotein degradation. Related codes cover defects in post-translational modification of lysosomal enzymes (E77.0), other disorders of glycoprotein metabolism (E77.8) and disorder of glycoprotein metabolism, unspecified (E77.9).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Before ICD-10, this condition was coded in ICD-9-CM as 271.8 (other specified disorders of carbohydrate transport and metabolism) and 272.7 (lipidoses).