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ICD-10-CM 2027 diagnosis code

E83.822ENPP1 deficiency causing autosomal recessive hypophosphatemic rickets type 2

✓ Billable / specific

E83.822 is a valid, billable ICD-10-CM code for enpp1 deficiency causing autosomal recessive hypophosphatemic rickets type 2. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: ENPP1 def cause autosom recess hypophosphate rickets type 2

Code last changed in FY2026 (effective October 1, 2025). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E83.822

E83.822 is the ICD-10-CM diagnosis code for ENPP1 deficiency causing autosomal recessive hypophosphatemic rickets type 2. It belongs to category E83 (disorders of mineral metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within E83.82 (disorders of pyrophosphate metabolism), E83.822 is specifically for ENPP1 deficiency causing autosomal recessive hypophosphatemic rickets type 2. Related codes cover generalized arterial calcification of infancy with unspecified genetic causality (E83.820), ENPP1 deficiency causing generalized arterial calcification of infancy (E83.821), ABCC6 deficiency causing generalized arterial calcification of infancy (E83.823), ABCC6 deficiency causing pseudoxanthoma elasticum (E83.824) and CD73 deficiency causing arterial calcification (E83.825).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2026, effective October 1, 2025.

Notes that apply from higher levels

Instructions written at a parent level also apply to E83.822.

› From E83 Disorders of mineral metabolism
Excludes1
  • dietary mineral deficiency (E58-E61)
  • parathyroid disorders (E20-E21)
  • vitamin D deficiency (E55.-)

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Alphabetic index entries

1 entries

Terms in the official ICD-10-CM index that lead to E83.822.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

MDC 10 · Endocrine, Nutritional and Metabolic Diseases and Disorders

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2026 (effective 10/1/2025): Added
  • No changes since FY2026.

Common questions about E83.822

Is E83.822 billable?

Yes. E83.822 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can E83.822 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict E83.822 as a principal diagnosis.

Is E83.822 a CC or MCC?

No. E83.822 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does E83.822 group to?

E83.822 is used in the MS-DRG v44.0 logic for MS-DRG 642 (Inborn and Other Disorders of Metabolism). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.