ICD-10-CM 2027
ICD-10 code for combined hyperlipemia
From the official ICD-10-CM alphabetic index entry “Hyperlipemia, hyperlipidemia › combined”. Page updated September 29, 2026.
About coding combined hyperlipemia
The ICD-10-CM code for combined hyperlipemia is E78.2 (Mixed hyperlipidemia). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on E78.2.
Within E78 (disorders of lipoprotein metabolism and other lipidemias), E78.2 is specifically for mixed hyperlipidemia. Related codes cover pure hypercholesterolemia (E78.0), pure hyperglyceridemia (E78.1), Hyperchylomicronemia (E78.3), other hyperlipidemia (E78.4), hyperlipidemia, unspecified (E78.5), lipoprotein deficiency (E78.6), disorders of bile acid and cholesterol metabolism (E78.7), other disorders of lipoprotein metabolism (E78.8) and 1 more.
Don't report E78.2 together with the conditions in its Excludes1 note: cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5) and familial combined hyperlipidemia (E78.49).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific combined hyperlipemia codes (official index)
- familial E78.49 — Other hyperlipidemia
Don't confuse with (Excludes1 for E78.2)
Common questions about combined hyperlipemia ICD-10 codes
What is the ICD-10 code for combined hyperlipemia?
- E78.2 — Mixed hyperlipidemia. More specific codes apply when the documentation supports them: E78.49.
What is the ICD-10 code for familial combined hyperlipemia?
- E78.49 — Other hyperlipidemia.
Is E78.2 billable?
- Yes. E78.2 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E78.2 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E78.2 as a principal diagnosis.
Is E78.2 a CC or MCC?
- No. E78.2 is neither a CC nor an MCC under MS-DRG v44.0.