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ICD-10-CM 2027 diagnosis code

E78Disorders of lipoprotein metabolism and other lipidemias

Not billable — use a more specific code

E78 is a header code, so it can't be reported by itself. Choose one of the 10 more specific codes beneath it.

Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS, effective October 1, 2026. Updated September 29, 2026. About our data

About E78

E78 is the ICD-10-CM diagnosis code for disorders of lipoprotein metabolism and other lipidemias. It belongs to block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 10 subcodes must be used instead.

To report this condition, pick the subcode that matches the documentation: E78.0 (hypercholesterolemia), E78.1 (hyperglyceridemia), E78.2 (hyperlipidemia), E78.3 (Hyperchylomicronemia), E78.4 (hyperlipidemia), E78.5 (unspecified), E78.6 (deficiency), E78.7 (metabolism) and 2 more.

Don't report E78 together with the conditions in its Excludes1 note: sphingolipidosis (E75.0-E75.3).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Specific codes under E78

Coding notes

Excludes1Not coded here — never report together with this code

Notes that apply from higher levels

Instructions written at a parent level also apply to E78.

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

Codes whose notes reference E78

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • No changes since FY2016.

Common questions about E78

Is E78 billable?

No. E78 is a header code. Report one of its more specific subcodes instead.