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ICD-10-CM 2027 diagnosis code

E78.4Other hyperlipidemia

Not billable — use a more specific code

E78.4 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it.

Code last changed in FY2019 (effective October 1, 2018). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E78.4

E78.4 is the ICD-10-CM diagnosis code for other hyperlipidemia. It belongs to category E78 (disorders of lipoprotein metabolism and other lipidemias), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.

Within E78, choose E78.4 (Other hyperlipidemia) only when documentation doesn't support a more specific option: pure hypercholesterolemia (E78.0), pure hyperglyceridemia (E78.1), mixed hyperlipidemia (E78.2), Hyperchylomicronemia (E78.3), hyperlipidemia, unspecified (E78.5), lipoprotein deficiency (E78.6), disorders of bile acid and cholesterol metabolism (E78.7), other disorders of lipoprotein metabolism (E78.8) and 1 more.

To report this condition, pick the subcode that matches the documentation: E78.41 (Lipoprotein(a)) and E78.49 (hyperlipidemia).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2019 (expanded into subcodes).

Before ICD-10, this condition was coded in ICD-9-CM as 272.4 (other and unspecified hyperlipidemia).

Specific codes under E78.4

Notes that apply from higher levels

Instructions written at a parent level also apply to E78.4.

› From E78 Disorders of lipoprotein metabolism and other lipidemias
Excludes1

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

ICD-9-CM equivalent

Converter →
  • 272.4Other and unspecified hyperlipidemiaapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • FY2019 (effective 10/1/2018): Expanded — no longer billable

Common questions about E78.4

Is E78.4 billable?

No. E78.4 is a header code. Report one of its more specific subcodes instead.

What is the ICD-9 code for E78.4?

The CMS General Equivalence Mappings map E78.4 to ICD-9-CM 272.4.