ICD-10-CM 2027
ICD-10 code for disease syndrome wasting
From the official ICD-10-CM alphabetic index entry “Wasting › disease (syndrome)”. Page updated September 29, 2026.
About coding disease syndrome wasting
The ICD-10-CM code for disease syndrome wasting is E88.A (Wasting disease (syndrome) due to underlying condition). The official index lists 3 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E88.A.
Within E88 (other and unspecified metabolic disorders), E88.A is specifically for wasting disease (syndrome) due to underlying condition. Related codes cover disorders of plasma-protein metabolism, not elsewhere classified (E88.0), lipodystrophy, not elsewhere classified (E88.1), Lipomatosis, not elsewhere classified (E88.2), tumor lysis syndrome (E88.3), mitochondrial metabolism disorders (E88.4), other specified metabolic disorders (E88.8) and metabolic disorder, unspecified (E88.9).
Don't report E88.A together with the conditions in its Excludes1 note: cachexia NOS (R64) and nutritional marasmus (E41).
The conditions in its Excludes2 note aren't part of E88.A, but may be coded alongside it if the patient has both: failure to thrive (R62.51, R62.7).
More specific disease syndrome wasting codes (official index)
Don't confuse with (Excludes1 for E88.A)
Common questions about disease syndrome wasting ICD-10 codes
What is the ICD-10 code for disease syndrome wasting?
- E88.A — Wasting disease (syndrome) due to underlying condition. More specific codes apply when the documentation supports them: E43, E41, E88.A.
Is E88.A billable?
- Yes. E88.A is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E88.A be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is E88.A a CC or MCC?
- No. E88.A is neither a CC nor an MCC under MS-DRG v44.0.