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ICD-10-CM 2027 diagnosis code

D48.19Other specified neoplasm of uncertain behavior of connective and other soft tissue

✓ Billable / specific

D48.19 is a valid, billable ICD-10-CM code for other specified neoplasm of uncertain behavior of connective and other soft tissue. It can be reported on claims for dates of service from October 1, 2026 – September 30, 2027.Short description: Oth neoplasm of uncertain behavior of connctv/soft tiss

Looking up by condition? See ICD-10 code for Myofibromatosis.

Code last changed in FY2024 (effective October 1, 2023). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About D48.19

D48.19 is the ICD-10-CM diagnosis code for other specified neoplasm of uncertain behavior of connective and other soft tissue. It belongs to category D48 (neoplasm of uncertain behavior of other and unspecified sites), block D37-D48 (neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes) and chapter 2 (neoplasms). It is billable, so it can be reported on its own for dates of service from October 1, 2026 through September 30, 2027.

Within D48.1, choose D48.19 (Other specified neoplasm of uncertain behavior of connective and other soft tissue) only when documentation doesn't support a more specific option: Desmoid tumor (D48.11).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 564 (Other Musculoskeletal System and Connective Tissue Diagnoses with MCC, relative weight 1.4908), DRG 565 (Other Musculoskeletal System and Connective Tissue Diagnoses with CC, relative weight 0.9783) and DRG 566 (Other Musculoskeletal System and Connective Tissue Diagnoses without CC/MCC, relative weight 0.7378), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

It was added in FY2024, effective October 1, 2023.

Notes that apply from higher levels

Instructions written at a parent level also apply to D48.19.

› From D48.1 Neoplasm of uncertain behavior of connective and other soft tissue
Excludes1
  • neoplasm of uncertain behavior of articular cartilage (D48.0)
  • neoplasm of uncertain behavior of cartilage of larynx (D38.0)
  • neoplasm of uncertain behavior of cartilage of nose (D38.5)
  • neoplasm of uncertain behavior of connective tissue of breast (D48.6-)
› From D48 Neoplasm of uncertain behavior of other and unspecified sites
Excludes1
  • neurofibromatosis (nonmalignant) (Q85.0-)

Broader instructions also apply from D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes and Chapter 2: Neoplasms.

Alphabetic index entries

6 entries

Terms in the official ICD-10-CM index that lead to D48.19.

MS-DRG v44.0 grouping

All DRGs →

Inpatient MS-DRGs this diagnosis can group to, as the principal or a secondary diagnosis, depending on the rest of the claim.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2024 (effective 10/1/2023): Added
  • No changes since FY2024.

Common questions about D48.19

Is D48.19 billable?

Yes. D48.19 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D48.19 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D48.19 as a principal diagnosis.

Is D48.19 a CC or MCC?

No. D48.19 is neither a CC nor an MCC under MS-DRG v44.0.

What DRG does D48.19 group to?

D48.19 is used in the MS-DRG v44.0 logic for MS-DRG 564 (Other Musculoskeletal System and Connective Tissue Diagnoses with MCC), MS-DRG 565 (Other Musculoskeletal System and Connective Tissue Diagnoses with CC) and MS-DRG 566 (Other Musculoskeletal System and Connective Tissue Diagnoses without CC/MCC). Which one applies depends on whether it is the principal diagnosis and on the rest of the claim.