ICD-10-CM 2027 diagnosis code
E72.8Other specified disorders of amino-acid metabolism
E72.8 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it.
Code last changed in FY2019 (effective October 1, 2018). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E72.8
E72.8 is the ICD-10-CM diagnosis code for other specified disorders of amino-acid metabolism. It belongs to category E72 (other disorders of amino-acid metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.
Within E72, choose E72.8 (Other specified disorders of amino-acid metabolism) only when documentation doesn't support a more specific option: disorders of amino-acid transport (E72.0), disorders of sulfur-bearing amino-acid metabolism (E72.1), disorders of urea cycle metabolism (E72.2), disorders of lysine and hydroxylysine metabolism (E72.3), disorders of ornithine metabolism (E72.4), disorders of glycine metabolism (E72.5) and disorder of amino-acid metabolism, unspecified (E72.9).
To report this condition, pick the subcode that matches the documentation: E72.81 (metabolism) and E72.89 (metabolism).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2019 (expanded into subcodes).
Before ICD-10, this condition was coded in ICD-9-CM as 270.7 (other disturbances of straight-chain amino-acid metabolism) and 270.8 (other specified disorders of amino-acid metabolism).
Specific codes under E72.8
Notes that apply from higher levels
Instructions written at a parent level also apply to E72.8.
Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.
ICD-9-CM equivalent
Converter →- 270.7Other disturbances of straight-chain amino-acid metabolismapproximate
- 270.8Other specified disorders of amino-acid metabolismapproximate
From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- FY2019 (effective 10/1/2018): Expanded — no longer billable