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ICD-10-CM 2027 diagnosis code

E72.8Other specified disorders of amino-acid metabolism

Not billable — use a more specific code

E72.8 is a header code, so it can't be reported by itself. Choose one of the 2 more specific codes beneath it.

Code last changed in FY2019 (effective October 1, 2018). Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data

About E72.8

E72.8 is the ICD-10-CM diagnosis code for other specified disorders of amino-acid metabolism. It belongs to category E72 (other disorders of amino-acid metabolism), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 2 subcodes must be used instead.

Within E72, choose E72.8 (Other specified disorders of amino-acid metabolism) only when documentation doesn't support a more specific option: disorders of amino-acid transport (E72.0), disorders of sulfur-bearing amino-acid metabolism (E72.1), disorders of urea cycle metabolism (E72.2), disorders of lysine and hydroxylysine metabolism (E72.3), disorders of ornithine metabolism (E72.4), disorders of glycine metabolism (E72.5) and disorder of amino-acid metabolism, unspecified (E72.9).

To report this condition, pick the subcode that matches the documentation: E72.81 (metabolism) and E72.89 (metabolism).

It has been part of ICD-10-CM since the code set took effect on October 1, 2015, and changed in FY2019 (expanded into subcodes).

Before ICD-10, this condition was coded in ICD-9-CM as 270.7 (other disturbances of straight-chain amino-acid metabolism) and 270.8 (other specified disorders of amino-acid metabolism).

Specific codes under E72.8

Notes that apply from higher levels

Instructions written at a parent level also apply to E72.8.

› From E72 Other disorders of amino-acid metabolism
Excludes1
  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.

ICD-9-CM equivalent

Converter →
  • 270.7Other disturbances of straight-chain amino-acid metabolismapproximate
  • 270.8Other specified disorders of amino-acid metabolismapproximate

From the CMS 2018 General Equivalence Mappings (GEMs), the final GEMs release.

Code history

  1. 2016
  2. 2017
  3. 2018
  4. 2019
  5. 2020
  6. 2021
  7. 2022
  8. 2023
  9. 2024
  10. 2025
  11. 2026
  12. 2027
  • FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
  • FY2019 (effective 10/1/2018): Expanded — no longer billable

Common questions about E72.8

Is E72.8 billable?

No. E72.8 is a header code. Report one of its more specific subcodes instead.

What is the ICD-9 code for E72.8?

The CMS General Equivalence Mappings map E72.8 to ICD-9-CM 270.7 and 270.8.