ICD-10-CM 2027 diagnosis code
E72Other disorders of amino-acid metabolism
E72 is a header code, so it can't be reported by itself. Choose one of the 8 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E72
E72 is the ICD-10-CM diagnosis code for other disorders of amino-acid metabolism. It belongs to block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 8 subcodes must be used instead.
To report this condition, pick the subcode that matches the documentation: E72.0 (transport), E72.1 (metabolism), E72.2 (metabolism), E72.3 (metabolism), E72.4 (metabolism), E72.5 (metabolism), E72.8 (metabolism) and E72.9 (unspecified).
Don't report E72 together with the conditions in its Excludes1 note: aromatic amino-acid metabolism (E70.-), branched-chain amino-acid metabolism (E71.0-E71.2), fatty-acid metabolism (E71.3), purine and pyrimidine metabolism (E79.-) and 1 more.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under E72
- E72.0Disorders of amino-acid transport
- E72.1Disorders of sulfur-bearing amino-acid metabolism
- E72.2Disorders of urea cycle metabolism
- E72.3Disorders of lysine and hydroxylysine metabolismBillable
- E72.4Disorders of ornithine metabolismBillable
- E72.5Disorders of glycine metabolism
- E72.8Other specified disorders of amino-acid metabolism
- E72.9Disorder of amino-acid metabolism, unspecifiedBillable
Coding notes
Notes that apply from higher levels
Instructions written at a parent level also apply to E72.
Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.
Codes whose notes reference E72
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E72
Is E72 billable?
- No. E72 is a header code. Report one of its more specific subcodes instead.