ICD-10-CM 2027 diagnosis code
E75.2Other sphingolipidosis
E75.2 is a header code, so it can't be reported by itself. Choose one of the 9 more specific codes beneath it.
Code unchanged since ICD-10-CM took effect on October 1, 2015. Source: official FY2027 ICD-10-CM release from CDC/NCHS and CMS. Page updated September 29, 2026. About our data
About E75.2
E75.2 is the ICD-10-CM diagnosis code for other sphingolipidosis. It belongs to category E75 (disorders of sphingolipid metabolism and other lipid storage disorders), block E70-E88 (metabolic disorders) and chapter 4 (endocrine, nutritional and metabolic diseases). It is a header code, so it can't be reported by itself; one of its 9 subcodes must be used instead.
Within E75, choose E75.2 (Other sphingolipidosis) only when documentation doesn't support a more specific option: GM2 gangliosidosis (E75.0), other and unspecified gangliosidosis (E75.1), sphingolipidosis, unspecified (E75.3), Neuronal ceroid lipofuscinosis (E75.4), other lipid storage disorders (E75.5) and lipid storage disorder, unspecified (E75.6).
To report this condition, pick the subcode that matches the documentation: E75.21 (disease), E75.22 (disease), E75.23 (disease), E75.24 (disease), E75.25 (leukodystrophy), E75.26 (deficiency), E75.27 (disease), E75.28 (disease) and 1 more.
Don't report E75.2 together with the conditions in its Excludes1 note: adrenoleukodystrophy [Addison-Schilder] (E71.528).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
Specific codes under E75.2
- E75.21Fabry (-Anderson) diseaseBillable
- E75.22Gaucher diseaseBillable
- E75.23Krabbe diseaseBillable
- E75.24Niemann-Pick disease
- E75.240Niemann-Pick disease type ABillable
- E75.241Niemann-Pick disease type BBillable
- E75.242Niemann-Pick disease type CBillable
- E75.243Niemann-Pick disease type DBillable
- E75.244Niemann-Pick disease type A/BBillable
- E75.248Other Niemann-Pick diseaseBillable
- E75.249Niemann-Pick disease, unspecifiedBillable
- E75.25Metachromatic leukodystrophyBillable
- E75.26Sulfatase deficiencyBillable
- E75.27Pelizaeus-Merzbacher diseaseBillable
- E75.28Canavan diseaseBillable
- E75.29Other sphingolipidosisBillable
Coding notes
- adrenoleukodystrophy [Addison-Schilder] (E71.528)
Notes that apply from higher levels
Instructions written at a parent level also apply to E75.2.
Broader instructions also apply from E70-E88 Metabolic disorders and Chapter 4: Endocrine, nutritional and metabolic diseases.
Code history
- 2016
- 2017
- 2018
- 2019
- 2020
- 2021
- 2022
- 2023
- 2024
- 2025
- 2026
- 2027
- FY2016 (effective 10/1/2015): Added (first year of ICD-10-CM)
- No changes since FY2016.
Common questions about E75.2
Is E75.2 billable?
- No. E75.2 is a header code. Report one of its more specific subcodes instead.